Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2017192606) METHODS OF PRODUCING SPECIALIZED CARDIO-LIKE CELLS FROM STEM CELL
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2017/192606 International Application No.: PCT/US2017/030665
Publication Date: 09.11.2017 International Filing Date: 02.05.2017
IPC:
C12N 5/073 (2010.01) ,C12N 5/077 (2010.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07
Animal cells or tissues
071
Vertebrate cells or tissues, e.g. human cells or tissues
073
Embryonic cells or tissues; Foetal cells or tissues
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07
Animal cells or tissues
071
Vertebrate cells or tissues, e.g. human cells or tissues
077
Mesenchymal cells, e.g. bone cells, cartilage cells, marrow stromal cells, fat cells or muscle cells
Applicants:
EMORY UNIVERSITY [US/US]; Office of Technology Transfer 1599 Clifton Road NE, 4th Floor Atlanta, Georgia 30322, US
CHILDREN'S HEALTHCARE OF ATLANTA, INC. [US/US]; 1600 Tullie Circle NE Atlanta, Georgia 30329, US
Inventors:
CHO, Hee Cheol; US
Agent:
MASON, James C.; US
FRITTS, Laura; US
ISAACS, Randi; US
SHERER, Todd; US
Priority Data:
62/330,50602.05.2016US
62/420,90411.11.2016US
Title (EN) METHODS OF PRODUCING SPECIALIZED CARDIO-LIKE CELLS FROM STEM CELL
(FR) PROCÉDÉS DE PRODUCTION DE CELLULES DE TYPE CARDIAQUE SPÉCIALISÉES À PARTIR DE CELLULES SOUCHES
Abstract:
(EN) This disclosure relates to method of differentiating stem cells to specific cardiac-like cells. In certain embodiments, the disclosure contemplates methods of generating left ventricular-like cells and the atrial-like cells by timing the exposure of dividing stem cells to retinoic acid (RA) or retinoic acid receptor inhibitors.
(FR) L'invention concerne un procédé de différenciation de cellules souches en cellules spécifiques de type cardiaque. Dans certains modes de réalisation, l'invention concerne des procédés de génération de cellules de type ventriculaire gauche et de cellules de type auriculaire par le minutage de l'exposition de cellules souches en cours de division à de l'acide rétinoïque (RA) ou à des inhibiteurs du récepteur de l'acide rétinoïque.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)