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1. (WO2017191234) PHARMACEUTICAL CARRIERS CONTAINING MIRNAS FOR USE IN THE TREATMENT OF FIBROTIC DISEASES CAUSED BY HYPERGLYCEMIA
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Pub. No.: WO/2017/191234 International Application No.: PCT/EP2017/060612
Publication Date: 09.11.2017 International Filing Date: 04.05.2017
IPC:
A61K 48/00 (2006.01) ,A61K 35/28 (2015.01) ,A61K 35/407 (2015.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48
Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
12
Materials from mammals or birds
28
Marrow; Spleen
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
12
Materials from mammals or birds
37
Digestive system
407
Liver
Applicants:
UNICYTE EV AG [CH/CH]; Aawasserstrasse 2 CH-6370 OBERDORF, CH
Inventors:
BRIZZI, Maria Felice; IT
CAMUSSI, Giovanni; IT
Agent:
COMOGLIO, Elena; IT
JACOBACCI, Guido; IT
QUINTERNO, Giuseppe; IT
RAMBELLI, Paolo; IT
GERBINO, Angelo; IT
FIORAVANTI, Corrado; IT
DEAMBROGI, Edgardo; IT
RONDANO, Davide; IT
VANZINI, Christian; IT
Priority Data:
16168546.606.05.2016EP
Title (EN) PHARMACEUTICAL CARRIERS CONTAINING MIRNAS FOR USE IN THE TREATMENT OF FIBROTIC DISEASES CAUSED BY HYPERGLYCEMIA
(FR) SUPPORTS PHARMACEUTIQUES CONTENANT DES MIARN POUR UTILISATION DANS LE TRAITEMENT DES MALADIES FIBROTIQUES PROVOQUÉES PAR L'HYPERGLYCÉMIE
Abstract:
(EN) The invention relates to a new therapeutic application of pharmaceutically acceptable carriers containing miR222. In particular, the invention relates to the use of extracellular vesicles (EVs) which contain the microRNA miR222, in the treatment of fibrotic disease caused by hyperglycaemia, such as diabetic nephropathy and/or renal fibrosis.
(FR) L'invention concerne une nouvelle application thérapeutique de supports de qualité pharmaceutique contenant du miR222. En particulier, l'invention concerne l'utilisation de vésicules extracellulaires qui contiennent le microARN miR222, dans le traitement d'une maladie fibrotique provoquée par l'hyperglycémie, telle que la néphropathie diabétique et/ou la fibrose rénale.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)