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1. (WO2017189965) PROCESSES FOR GENERATING SUPERIOR ANTI-TUMOR T-CELL EFFECTOR AND MEMORY CELLS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/189965    International Application No.:    PCT/US2017/030062
Publication Date: 02.11.2017 International Filing Date: 28.04.2017
IPC:
A61K 35/17 (2015.01), C12N 5/0783 (2010.01), A61P 35/00 (2006.01)
Applicants: MUSC FOUNDATION FOR RESEARCH DEVELOPMENT [US/US]; 19 Hagood Avenue, Suite 909 Charleston, SC 29425 (US)
Inventors: MEHROTRA, Shikhar; (US).
NISHIMURA, Michael, I.; (US).
KESARWANI, Pravin; (US).
CHATTERJEE, Shilpak; (US)
Agent: NGUYEN, Quang, D.; (US).
CHEN, Ming; (US).
CAMPBELL, Christopher; (US).
ALLEN, Justin; (US).
ARTIS, Ryan; (US)
Priority Data:
62/328,780 28.04.2016 US
Title (EN) PROCESSES FOR GENERATING SUPERIOR ANTI-TUMOR T-CELL EFFECTOR AND MEMORY CELLS
(FR) PROCÉDÉS DE GÉNÉRATION DE CELLULES MÉMOIRE ET EFFECTRICES TYPE LYMPHOCYTES T ANTI-TUMORALES SUPÉRIEURES
Abstract: front page image
(EN)The present invention relates to an adoptive T cell therapy using cells generated by genetically or biochemically reprogramming T cells to produce T memory stem cells (Tscm) that persist longer in vivo and are superior anti-tumor effector cells.
(FR)La présente invention concerne une thérapie par transfert adoptif de lymphocytes T utilisant des cellules générées par reprogrammation génétique ou biochimique de lymphocytes T pour produire des cellules souches mémoire T (Tscm) qui persistent plus longtemps in vivo et qui sont des cellules effectrices antitumorales supérieures.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)