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1. (WO2017189891) METHODS FOR TREATING ZIKA VIRAL INFECTIONS AND ASSOCIATED COMPLICATIONS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/189891    International Application No.:    PCT/US2017/029918
Publication Date: 02.11.2017 International Filing Date: 27.04.2017
IPC:
C07K 7/00 (2006.01), C07K 7/08 (2006.01), C07K 16/10 (2006.01), A61K 38/10 (2006.01)
Applicants: MIDDLE TENNESSEE STATE UNIVERSITY [US/US]; 1301 E. Main St. Murfreesboro, TN 37132 (US).
BODIE, Neil, M. [US/US]; (US).
ALTMAN, Elliot [US/US]; (US).
PARK, Hyo [US/US]; (US)
Inventors: BODIE, Neil, M.; (US).
ALTMAN, Elliot; (US).
PARK, Hyo; (US)
Agent: ARNESON, Laura, N.; (US)
Priority Data:
62/328,416 27.04.2016 US
Title (EN) METHODS FOR TREATING ZIKA VIRAL INFECTIONS AND ASSOCIATED COMPLICATIONS
(FR) MÉTHODES DE TRAITEMENT D'INFECTIONS PAR LE VIRUS ZIKA ET DE COMPLICATIONS ASSOCIÉES
Abstract: front page image
(EN)Polypeptides and other compounds that can bind specifically to the CH2-CH3 cleft of an immunoglobulin molecule, as well as methods for using such polypeptides and compounds to inhibit Fc-mediated immune complex formation in viral infection, are described. For example, polypeptides and other compounds can be used to inhibit immune complex formation in a subject who has been diagnosed as having or is suspected of having a Zika virus infection.
(FR)Cette invention concerne des polypeptides et autres composés qui se lient spécifiquement à la fissure CH2-CH3 d'une molécule d'immunoglobuline, ainsi que des méthodes d'utilisation de ces polypeptides et composés pour inhiber la formation d'un complexe immun à médiation Fc dans l'infection virale. Par exemple, des polypeptides et d'autres composés peuvent être utilisés pour inhiber la formation de complexes immuns chez un sujet qui a été diagnostiqué comme atteint ou suspecté d’être atteint d’une infection par le virus Zika.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)