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1. (WO2017189692) TREATMENT OF TUMORS WITH INHIBITORS OF CXCL12 SIGNALING AND SUBTHERAPEUTIC AMOUNTS OF CHEMOTHERAPEUTIC AGENTS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/189692    International Application No.:    PCT/US2017/029582
Publication Date: 02.11.2017 International Filing Date: 26.04.2017
IPC:
A61K 31/33 (2006.01), A61K 31/337 (2006.01), A61K 31/395 (2006.01), A61K 38/19 (2006.01), A61P 35/00 (2006.01), C07D 257/00 (2006.01)
Applicants: THE GENERAL HOSPITAL CORPORATION [US/US]; 55 Fruit Street Boston, Massachusetts 02114 (US)
Inventors: POZNANSKY, Mark C.; (US).
REEVES, Patrick; (US)
Agent: Myers Bigel, P.A.; P.O. Box 37428 Raleigh, North Carolina 27627 (US)
Priority Data:
62/327,958 26.04.2016 US
Title (EN) TREATMENT OF TUMORS WITH INHIBITORS OF CXCL12 SIGNALING AND SUBTHERAPEUTIC AMOUNTS OF CHEMOTHERAPEUTIC AGENTS
(FR) TRAITEMENT DE TUMEURS AVEC DES INHIBITEURS DE LA SIGNALISATION CXCL12 ET DES QUANTITÉS SUBTHÉRAPEUTIQUES D'AGENTS CHIMIOTHÉRAPEUTIQUES
Abstract: front page image
(EN)The invention described herein relates to methods for treating cancer in a subject by administering an effective amount of a CXCL12 signaling inhibitor and a subtherapeutic amount of an anti-cancer agent, e.g., a chemotherapeutic agent.
(FR)La présente invention concerne des procédés de traitement du cancer chez un sujet par administration d'une quantité efficace d'un inhibiteur de signalisation CXCL12 et d'une quantité subthérapeutique d'un agent anticancéreux, par exemple un agent chimiothérapeutique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)