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1. (WO2017189692) TREATMENT OF TUMORS WITH INHIBITORS OF CXCL12 SIGNALING AND SUBTHERAPEUTIC AMOUNTS OF CHEMOTHERAPEUTIC AGENTS

Pub. No.:    WO/2017/189692    International Application No.:    PCT/US2017/029582
Publication Date: Fri Nov 03 00:59:59 CET 2017 International Filing Date: Thu Apr 27 01:59:59 CEST 2017
IPC: A61K 31/33
A61K 31/337
A61K 31/395
A61K 38/19
A61P 35/00
C07D 257/00
Applicants: THE GENERAL HOSPITAL CORPORATION
Inventors: POZNANSKY, Mark C.
REEVES, Patrick
Title: TREATMENT OF TUMORS WITH INHIBITORS OF CXCL12 SIGNALING AND SUBTHERAPEUTIC AMOUNTS OF CHEMOTHERAPEUTIC AGENTS
Abstract:
The invention described herein relates to methods for treating cancer in a subject by administering an effective amount of a CXCL12 signaling inhibitor and a subtherapeutic amount of an anti-cancer agent, e.g., a chemotherapeutic agent.