Search International and National Patent Collections

1. (WO2017189512) RESONATOR FOR DETECTING SINGLE MOLECULE BINDING

Pub. No.:    WO/2017/189512    International Application No.:    PCT/US2017/029311
Publication Date: Fri Nov 03 00:59:59 CET 2017 International Filing Date: Wed Apr 26 01:59:59 CEST 2017
IPC: G01N 15/10
G01H 1/14
G01H 13/00
G01N 29/02
Applicants: QORVO US, INC.
Inventors: WEBSTER, James
Title: RESONATOR FOR DETECTING SINGLE MOLECULE BINDING
Abstract:
Various embodiments of an apparatus for measuring binding kinetics of an interaction of an analyte material present in a fluid sample are disclosed. The apparatus includes a sensing resonator having at least one binding site for the analyte material; actuation circuitry adapted to drive the sensing resonator into an oscillating motion; measurement circuitry coupled to the sensing resonator and adapted to measure an output signal of the sensing resonator representing resonance characteristics of the oscillating motion of the sensing resonator; and a controller coupled to the actuation and measurement circuitry, wherein the controller is adapted to detect an individual binding event between the at least one binding site and a molecule of the analyte material.