Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2017189294) METHOD AND KIT FOR IDENTIFYING LUPUS ANTICOAGULANT (LA) ASSOCIATED WITH ANTIPHOSPHOLIPID SYNDROME
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2017/189294 International Application No.: PCT/US2017/028286
Publication Date: 02.11.2017 International Filing Date: 19.04.2017
IPC:
G01N 33/86 (2006.01) ,G01N 33/564 (2006.01) ,C12Q 1/56 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
86
involving blood coagulating time
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
564
for pre-existing immune complex or autoimmune disease
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
56
involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
Applicants:
INSTRUMENTATION LABORATORY COMPANY [US/US]; 180 Hartwell Road Bedford, Massachusetts 01730, US
Inventors:
BOTTENUS, Ralph, E.; US
CAO, Zhenghua; US
Agent:
MOORE, Ronda, P.; US
COHEN, Jerry; US
GOMES, David, W.; US
CHOW, Stephen, Y.; US
FOLEY, Shawn, P.; US
JOBSE, Bruce, D.; US
MILLS, Steven, M.; US
SERIO, John, C.; US
SUSAN, Janine, M.; US
LOPEZ, Orlando; US
HAMILTON III, John, A.; US
MARAIA, Joseph, M.; US
GROLNIC, Marlo, Schepper; US
GOLDMAN, Gabriel; US
HASAN, Shahid; US
Priority Data:
62/327,02825.04.2016US
Title (EN) METHOD AND KIT FOR IDENTIFYING LUPUS ANTICOAGULANT (LA) ASSOCIATED WITH ANTIPHOSPHOLIPID SYNDROME
(FR) PROCÉDÉ ET KIT POUR IDENTIFIER UN ANTICOAGULANT LUPIQUE (LA) ASSOCIÉ AU SYNDROME DES ANTIPHOSPHOLIPIDES
Abstract:
(EN) The invention described herein relates to a method and kit for the diagnosis of antiphospholipid syndrome in patients, wherein a coagulation inhibitor and normal pooled plasma mixture reduce the factor deficiency effect of patient plasma, and coagulation inhibitor interference in patient plasma, and increases specificity and the sensitivity for detecting lupus anticoagulants in the patient's blood in a phospholipid-dependent clotting assay.
(FR) La présente invention concerne un procédé et un kit pour le diagnostic du syndrome des antiphospholipides chez des patients, dans lesquels un inhibiteur de coagulation et un mélange de plasma normal groupé réduisent l'effet de déficience en facteur de plasma de patient, et l'interférence d'inhibiteurs de coagulation dans le plasma du patient, et augmente la spécificité et la sensibilité pour détecter des anticoagulants lupiques dans le sang du patient dans un essai de coagulation dépendant des phospholipides.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)