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1. (WO2017186894) PYRROLOBENZODIAZEPINE CONJUGATES AND THEIR USE FOR THE TREATMENT OF CANCER

Pub. No.:    WO/2017/186894    International Application No.:    PCT/EP2017/060150
Publication Date: Fri Nov 03 00:59:59 CET 2017 International Filing Date: Sat Apr 29 01:59:59 CEST 2017
IPC: C07D 487/04
A61K 47/68
A61P 35/00
C07K 16/28
Applicants: MEDIMMUNE LIMITED
Inventors: HOWARD, Philip Wilson
CAILLEAU, Thais
Title: PYRROLOBENZODIAZEPINE CONJUGATES AND THEIR USE FOR THE TREATMENT OF CANCER
Abstract:
A conjugate of formula (I): L -(DL)p, wherein L is a Ligand unit, D is a Drug Linker unit of formula (II), wherein p is an integer of from 1 to 20.