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1. (WO2017186719) MICRORNA BIOMARKERS IN BLOOD FOR DIAGNOSIS OF ALZHEIMER'S DISEASE
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/186719    International Application No.:    PCT/EP2017/059800
Publication Date: 02.11.2017 International Filing Date: 25.04.2017
IPC:
C12Q 1/68 (2006.01)
Applicants: INSTYTUT BIOLOGII DOSWIADCZALNEJ IM. MARCELEGO NENCKIEGO POLSKA AKADEMIA NAUK [PL/PL]; Ludwika Pasteura 3 02-093 Warszawa (PL).
BIOTECH INNOVATIONS SPÓLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA [PL/PL]; ul. Ksiecia Trojdena 4 02-109 Warszawa (PL)
Inventors: WOJDA, Urszula; (PL).
LASKOWSKA-KASZUB, Katarzyna; (PL).
GABRYELEWICZ, Tomasz; (PL).
KUZNICKI, Jacek; (PL)
Agent: OGLE, James; HOFFMANN EITLE PATENT- UND RECHTSANWÄLTE PARTMBB Arabellastraße 30 81925 Munich (DE).
ZANGS, Rainer E.; (DE).
KINDLER, Matthias; (DE).
FRANK, Veit Peter; (DE).
POLZ, Leo; (DE).
STEIN-DRÄGER, Christiane; (DE).
AVERY, Stephen John; (DE).
LETHEM, David James; (DE).
MARSH, Roy David; (DE).
MITCHELL, Alan; (DE).
FURLONG, Christopher Heinrich; (DE).
BAUSCH, Thorsten; (DE).
TAORMINO, Joseph Paul; (DE).
KLUSMANN, Peter; (DE).
SCHWEIGHART, Peter; (DE).
WOLF, Matthias; (DE).
SIEGERT, Georg; (DE).
MAYRHOFER, Stefan; (DE).
STRATMANN, Klemens; (DE).
WIEDEMANN, Peter; (DE).
VON KUROWSKI, Lorenz; (DE).
BECHER, Claus Thomas; (DE).
SPILGIES, Jan-Hendrik; (DE).
RENKEN, Joachim; (DE).
ENGELHARD, Elisabeth; (DE).
BACHELIN, Karl Martin Raimund; (DE).
DISSER, Stephan; (DE).
VAN BOUWELEN, Franciscus Maria; (DE).
FÜCHSLE, Kathrin; (DE).
CIESLA, Ulrike; (DE).
SCHÖN, Anne Katrin; (DE).
VOCKE, Henrik; (DE).
GÖRG, Andreas; (DE).
GARBERG, Morten; (DE).
RUSSELL, John Alistair; (DE).
SPROSTON, David; (DE).
THIRLWELL, Karen; (DE).
SCHEIBLE, Dominik; (DE).
VOS, Bianca-Lucia; (DE).
DOUXCHAMPS, Nicolas; (DE).
STEFFERL, Andreas; (DE).
GOLLER, Daniel; (DE).
PRUSS, Timo; (DE).
WERNER-JONES, Leonard L.; (DE).
BACCELLI, Michele; (DE).
MÜLLER, Markus Georg; (DE).
MUNCKE, Nadja; (DE).
CORNEO, Giovanni; (DE).
STREGE, Christine; (DE).
DRAGOSAVAC, Marko; (DE).
BIRKETT, Matthew; (DE).
ZILLIES, Jan Carl; (DE).
GROHS, Daniel; (DE).
MULHERN, Declan; (DE).
GRIMM, Stephan; (DE).
TILLMANN, Volker; (DE).
OGLE, James Matthew; (DE).
GLAS, Johannes Dominik; (DE).
STEINMÜLLER, Stephan; (DE).
BENEDETTO, Marco; (DE).
LEVINE, Benjamin; (DE).
JONES, Mark A. G.; (DE).
GRAEBER, Jens; (DE).
FUSTER, Gustavo; (DE).
ESSER, Axel T.; (DE).
SCHIEREN, Roland; (DE).
RECKENTHÄLER, Peter; (DE).
CATANIA, Olivier; (DE).
DÖRFEL, Katrin; (DE).
WEINMANN, Lasse; (DE).
SASSE, Stefan; (DE)
Priority Data:
PL416956 25.04.2016 PL
PCT/IB2016/052440 29.04.2016 IB
Title (EN) MICRORNA BIOMARKERS IN BLOOD FOR DIAGNOSIS OF ALZHEIMER'S DISEASE
(FR) MICRO-ARN BIOMARQUEURS DANS LE SANG DESTINÉ AU DIAGNOSTIC DE LA MALADIE D’ALZHEIMER
Abstract: front page image
(EN)The present invention relates to panels of biomarker microRNAs for use in methods of diagnosing Alzheimer's disease and related diseases and conditions in a subject. The methods involve assessing the level of said biomarker microRNA(s) in subject blood sample. The invention also relates to kits comprising said panels of biomarker microRNAs, methods of diagnosing Alzheimer's disease and to the use of said panels of biomarker microRNAs in diagnosis.
(FR)La présente invention concerne des panels de micro-ARN biomarqueurs destinés à être utilisés dans les procédés de diagnostic de la maladie d’Alzheimer et des maladies et des états associés chez un sujet. Les procédés impliquent l’évaluation du niveau desdits micro-ARN biomarqueur(s) dans un échantillon de sang du sujet. L’invention concerne également des trousses comprenant lesdits panels de micro-ARN biomarqueurs, des procédés de diagnostic de la maladie d’Alzheimer et l’utilisation desdits panels de micro-ARN biomarqueurs dans le diagnostic.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)