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1. (WO2017186711) NOVEL COMPLEXES OF IMMUNOSTIMULATORY COMPOUNDS, AND USES THEREOF

Pub. No.:    WO/2017/186711    International Application No.:    PCT/EP2017/059781
Publication Date: Fri Nov 03 00:59:59 CET 2017 International Filing Date: Wed Apr 26 01:59:59 CEST 2017
IPC: A61K 31/7084
A61K 31/7076
A61K 31/708
A61K 33/42
A61K 9/00
A61P 35/00
A61P 31/00
Applicants: INVIVOGEN
Inventors: VERNEJOUL, Fabienne
BOULARAN, Cédric
DROCOURT, Daniel
LIOUX, Thierry
QUSHAIR, Grégory
ROMO, Jésus
TIRABY, Gérard
Title: NOVEL COMPLEXES OF IMMUNOSTIMULATORY COMPOUNDS, AND USES THEREOF
Abstract:
The present invention concerns the preparation of complexes formed between a cationic lipid and at least one of various cyclic dinucleotide (CDN) agonists of STING, and proposes uses of such complexes. Specifically, such complexes can be used to provide enhanced or distinct biological activities in vitro, ex vivo or in vivo, relative to use of the corresponding CDN component alone.