Search International and National Patent Collections

1. (WO2017185695) IN-VIVO TARGETED DRUG ADMINISTRATION DEVICE AND OPERATING METHOD

Pub. No.:    WO/2017/185695    International Application No.:    PCT/CN2016/103428
Publication Date: Fri Nov 03 00:59:59 CET 2017 International Filing Date: Thu Oct 27 01:59:59 CEST 2016
IPC: A61M 31/00
A61F 2/90
A61F 2/966
Applicants: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCES
中国科学院深圳先进技术研究院
SHANDONG UNIVERSITY
山东大学
Inventors: CAI, Feiyan
蔡飞燕
ZHANG, Pengfei
张鹏飞
LI, Fei
李飞
ZHENG, Hairong
郑海荣
MENG, Long
孟龙
YAN, Fei
严飞
WANG, Chen
王辰
Title: IN-VIVO TARGETED DRUG ADMINISTRATION DEVICE AND OPERATING METHOD
Abstract:
An in-vivo targeted drug administration device and a operating method. The device comprises a stent-type artificial acoustic structure (04), a stent-type artificial acoustic structure in-vivo delivery device (06), and an ultrasonic electronic device (02), wherein the stent-type artificial acoustic structure in-vivo delivery device (06) is used for delivering the stent-type artificial acoustic structure (04) into a blood vessel of a target lesion, and the stent-type artificial acoustic structure (04) is dilated and attached to the inner wall of the blood vessel; the ultrasonic electronic device (02) is used for transmitting ultrasonic waves in vitro to stimulate the stent-type artificial acoustic structure (04) to generate a local strong field on the surface thereof; the stent-type artificial acoustic structure (04) is preinstalled in the stent-type artificial acoustic structure in-vivo delivery device (06) and used for gathering drug particles injected into the blood vessel to the inner wall of the blood vessel by means of the local strong field on the surface of the stent-type artificial acoustic structure (04) when the stent-type artificial acoustic structure (04) is delivered into the blood vessel of the target lesion. By the technical solution, the drug particles are gathered in a noninvasive and targeted manner in the blood vessel by means of the in-vitro ultrasonic waves, and the accuracy of targeted drug administration to the target lesion of a human body is improved.