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1. (WO2017184968) METHODS OF SELECTING CANCER PATIENTS FOR TREATMENT WITH FARNESYLTRANSFERASE INHIBITORS
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Pub. No.: WO/2017/184968 International Application No.: PCT/US2017/028820
Publication Date: 26.10.2017 International Filing Date: 21.04.2017
IPC:
C12Q 1/68 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
Applicants:
KURA ONCOLOGY, INC. [US/US]; 11119 North Torrey Pines Road, Suite 125 La Jolla, CA 92037, US
Inventors:
GUALBERTO, Antonio; US
Agent:
RIEGER, Dale, L.; US
INSOGNA, Anthony, M.; US
ROWAN, Thomas, G.; US
FRIEBEL, Thomas, E.; US
ANTLER, Adriane, M.; US
Priority Data:
62/326,63922.04.2016US
Title (EN) METHODS OF SELECTING CANCER PATIENTS FOR TREATMENT WITH FARNESYLTRANSFERASE INHIBITORS
(FR) MÉTHODES DE SÉLECTION DE PATIENTS ATTEINTS DE CANCER POUR LE TRAITEMENT AVEC DES INHIBITEURS DE FARNÉSYLTRANSFÉRASE
Abstract:
(EN) The present invention relates to the field of molecular biology, cell biology, and cancer biology. Specifically, the present invention relates to methods of treating peripheral T-cell lymphoma ("PTCL") with a famesyltransferase inhibitor (FTI) that include determining whether the subject is likely to be responsive to the FTI treatment based on the PTCL subtypes and additional characteristics.
(FR) La présente invention concerne le domaine de la biologie moléculaire, de la biologie cellulaire, et de la biologie cancéreuse. Plus spécifiquement, la présente invention concerne des méthodes de traitement d'un lymphome T périphérique ("PTCL") avec un inhibiteur de farnésyltransférase (FTI) qui consistent à déterminer si le sujet est susceptible d'être sensible au traitement par FTI sur la base des sous-types du PTCL et de caractéristiques supplémentaires.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)