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1. (WO2017184786) CPF1 COMPLEXES WITH REDUCED INDEL ACTIVITY
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/184786    International Application No.:    PCT/US2017/028461
Publication Date: 26.10.2017 International Filing Date: 19.04.2017
IPC:
C12N 15/11 (2006.01), C12N 9/22 (2006.01), C12N 15/113 (2010.01), C12N 15/63 (2006.01)
Applicants: THE BROAD INSTITUTE INC. [US/US]; 415 Main Street Cambridge, MA 02142 (US).
MASSACHUSETTS INSTITUTE OF TECHNOLOGY [US/US]; 77 Massachusetts Ave. Cambridge, MA 02139 (US).
ZHANG, Feng [US/US]; (US).
ZETSCHE, Bernd [DE/US]; (US).
YAN, Winston [US/US]; (US).
SANJANA, Neville, Espi [US/US]; (US).
JONES, Sara [US/US]; (US)
Inventors: ZHANG, Feng; (US).
ZETSCHE, Bernd; (US).
YAN, Winston; (US).
SANJANA, Neville, Espi; (US).
JONES, Sara; (US)
Agent: KOWALSKI, Thomas, J.; (US).
LU, Deborah, L.; (US).
CASSON, Lawrence, P.; (US).
RUSSELL, Mark, W.; (US).
NGUYEN, Tinh, T.; (US)
Priority Data:
62/324,834 19.04.2016 US
Title (EN) CPF1 COMPLEXES WITH REDUCED INDEL ACTIVITY
(FR) COMPLEXES CPF1 À ACTIVITÉ D'INDEL RÉDUITE
Abstract: front page image
(EN)The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered DNA-targeting systems comprising a novel DNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA.
(FR)L'invention concerne des systèmes, des méthodes et des compositions de ciblage d'acides nucléiques. En particulier, l'invention concerne des systèmes de ciblage d'ADN non naturels ou génétiquement modifiés comprenant une nouvelle protéine effectrice CRISPR de ciblage d'ADN et au moins un composant d'acide nucléique de ciblage tel qu'un ARN guide.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)