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1. (WO2017184752) ANTI-FUNGAL COMPOUNDS

Pub. No.:    WO/2017/184752    International Application No.:    PCT/US2017/028390
Publication Date: Fri Oct 27 01:59:59 CEST 2017 International Filing Date: Thu Apr 20 01:59:59 CEST 2017
IPC: C07C 225/20
C07C 49/753
C07C 49/747
Applicants: SAINT LOUIS UNIVERSITY
RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
Inventors: DONLIN, Maureen, J.
TAVIS, John, Edwin
MURELLI, Ryan
MEYERS, Marvin, J.
Title: ANTI-FUNGAL COMPOUNDS
Abstract:
The present disclosure provides compounds of the formula (I), (II), (III), wherein the variables are as defined herein for use in the treatment of fungal infections. In some embodiments, the fungal infection is an infection of Cryptococcus neojormans fungus. Also provided herein are compositions comprising a compound of formula I, II, or III and a second anti-fungal agent.