WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2017184691) TRANSPOSASE COMPETITOR CONTROL SYSTEM
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/184691    International Application No.:    PCT/US2017/028293
Publication Date: 26.10.2017 International Filing Date: 19.04.2017
IPC:
C12Q 1/68 (2006.01)
Applicants: KAPA BIOSYSTEMS, INC. [US/US]; 200 Ballardvale Street Suite 250 Wilmington, Massachusetts 01887 (US)
Inventors: RANIK, Martin; (ZA).
BOURN, William; (ZA).
VAN DER WALT, Eric; (ZA).
HSIEH, Jennifer; (ZA).
DE BEER, Abre; (ZA).
UYS, Gerrida; (ZA).
MCEWAN, Paul; (ZA)
Agent: ELRIFI, Ivor R.; (US).
MILLER, Katherine; (US)
Priority Data:
62/324,683 19.04.2016 US
Title (EN) TRANSPOSASE COMPETITOR CONTROL SYSTEM
(FR) SYSTÈME DE CONTRÔLE D'UN COMPÉTITEUR DE TRANSPOSASE
Abstract: front page image
(EN)Disclosed is a method of fragmenting DNA comprising contacting a sample of target DNA with (a) a composition comprising an active transpososome, and (b) a composition comprising an inactive transpososome, under conditions suitable for transpososome activity, wherein a ratio of an amount of the inactive transpososome in the composition of (b) to an amount of the active transpososome in the composition of (a) determines the mean fragment size and a level of insertion bias.
(FR)L'invention concerne un procédé de fragmentation d'ADN comprenant la mise en contact d'un échantillon d'ADN cible avec (a) une composition comprenant un transpososome actif, et (b) une composition comprenant un transpososome inactif, dans des conditions appropriées à une activité transpososome, le rapport de la quantité de transpososome inactif dans la composition de (b) à la quantité de transpososome actif dans la composition de (a) déterminant la taille moyenne de fragment et un niveau de biais d'insertion.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)