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|1. (WO2017181943) PHARMACEUTICAL COMPOSITION CONTAINING PEITC AND USE THEREOF IN CANCER TREATMENT|
|Applicants:||JC (WUXI) COMPANY, INC.
|Title:||PHARMACEUTICAL COMPOSITION CONTAINING PEITC AND USE THEREOF IN CANCER TREATMENT|
Provided in the present invention is a use of PEITC for preparing a preparation or composition. The preparation or composition is used for: (a) altering the mutant p53 to restore the wild-type activity; (b) inhibiting the tumour cell proliferation caused by the mutant p53; (c) inducing apoptosis of mutant p53 tumour cells; and/or (d) preventing or treating diseases based on p53 mutations. Also provided in the present invention are a use of a p53 gene detection reagent, a kit comprising PEITC and the p53 gene detection reagent, and a method for non-therapeutically inhibiting tumour cells in vitro.