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1. (WO2017181934) USES OF ZOLEDRONIC ACID
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/181934    International Application No.:    PCT/CN2017/080879
Publication Date: 26.10.2017 International Filing Date: 18.04.2017
IPC:
A61K 31/675 (2006.01), A61K 31/436 (2006.01), A61K 31/366 (2006.01), A61P 35/00 (2006.01)
Applicants: NANJING UNIVERSITY [CN/CN]; No. 22 Hankou Road, Gulou Nanjing, Jiangsu 210093 (CN)
Inventors: XUE, Bin; (CN).
LI, Chaojun; (CN).
ZHAO, Dandan; (CN)
Agent: NANJING JINGWEI PATENT & TRADEMARK AGENCY CO., LTD; 12th FL.-B No. 179 Zhongshan Road, Gulou Nanjing, Jiangsu 210005 (CN)
Priority Data:
201610243342.5 19.04.2016 CN
201610459407.X 22.06.2016 CN
Title (EN) USES OF ZOLEDRONIC ACID
(FR) UTILISATIONS DE L’ACIDE ZOLÉDRONIQUE
(ZH) 唑来膦酸的用途
Abstract: front page image
(EN)Disclosed in the present invention are uses of zoledronic acid in the preparation of drugs related to pulmonary lymphangioleiomyomatosis diseases. The present invention provides new uses of zoledronic acid in drugs for treating the pulmonary lymphangioleiomyomatosis. The pulmonary lymphangioleiomyomatosis comprises nodular hyperplasia and diffuse hyperplasia of lung tissues and smooth muscles in the hilum of the lung. The zoledronic acid according to the present invention can effectively treat pulmonary lymphangioleiomyomatosis, and can effectively reduce recurrence of the pulmonary lymphangioleiomyomatosis in combination with rapamycin.
(FR)La présente invention concerne des utilisations de l'acide zolédronique dans la préparation de médicaments associés aux maladies pulmonaires de type lymphangioléiomyomatose. La présente invention concerne de nouvelles utilisations de l'acide zolédronique dans des médicaments destinés au traitement de la lymphangioléiomyomatose pulmonaire. La lymphangioléiomyomatose pulmonaire comprend une hyperplasie nodulaire et une hyperplasie diffuse des tissus pulmonaires et des muscles lisses dans le hile du poumon. L'acide zolédronique selon la présente invention peut efficacement traiter la lymphangioléiomyomatose pulmonaire, et peut efficacement réduire la récurrence de la lymphangioléiomyomatose pulmonaire en combinaison avec la rapamycine.
(ZH)本发明公开了唑来膦酸在制备肺部淋巴管平滑肌瘤病药物中的用途。本发明提出了唑来膦酸用于治疗肺淋巴管平滑肌瘤药物的新用途,所述肺部淋巴管平滑肌瘤包括肺组织以及肺门内的平滑肌结节性及弥漫性增生。根据本文发明唑来膦酸可以有效的治疗肺部淋巴管平滑肌瘤,并且联合雷帕霉素可以有效的较少肺部淋巴管平滑肌瘤的复发。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)