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1. (WO2017181187) METHOD OF TREATING RENAL CELL CARCINOMA USING N-(4-(6,7-DIMETHOXYQUINOLIN-4-YLOXY) PHENYL)-N'-(4-FLUOROPHENY)CYCLOPROPANE-1,1-DICARBOXAMIDE, (2S)-HYDROXYBUTANEDIOATE
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Pub. No.: WO/2017/181187 International Application No.: PCT/US2017/027965
Publication Date: 19.10.2017 International Filing Date: 17.04.2017
IPC:
A61K 31/47 (2006.01) ,A61K 31/16 (2006.01) ,A61P 35/00 (2006.01)
Applicants: EXELIXIS, INC.[US/US]; 210 East Grand Ave. South San Francisco, CA 94080, US
Inventors: AFTAB, Dana, T.; US
SCHWAB, Gisela; US
HESSEL, Colin; US
SCHEFFOLD, Christian; US
LACY, Steven; US
MILES, Dale; US
ARROYO, Alan; US
DEAN, Mark; US
Agent: BERVEN, Heidi, M.; US
Priority Data:
62/323,53615.04.2016US
62/323,54815.04.2016US
62/323,55615.04.2016US
62/324,15718.04.2016US
62/324,15818.04.2016US
62/324,17618.04.2016US
62/338,15418.05.2016US
62/338,19518.05.2016US
62/338,24018.05.2016US
62/338,26718.05.2016US
62/345,65203.06.2016US
62/457,47110.02.2017US
62/457,61310.02.2017US
62/457,67110.02.2017US
Title (EN) METHOD OF TREATING RENAL CELL CARCINOMA USING N-(4-(6,7-DIMETHOXYQUINOLIN-4-YLOXY) PHENYL)-N'-(4-FLUOROPHENY)CYCLOPROPANE-1,1-DICARBOXAMIDE, (2S)-HYDROXYBUTANEDIOATE
(FR) PROCÉDÉ DE TRAITEMENT DU CANCER À CELLULES RÉNALES À L'AIDE DE N-(4-(6,7-DIMÉTHOXYQUINOLIN-4-YLOXY) PHÉNYL)-N'-(4-FLUOROPHÉNY)CYCLOPROPANE-1,1-DICARBOXAMIDE, (2S)-HYDROXYBUTANEDIOATE
Abstract:
(EN) The present disclosure relates to a method of treating advanced renal cell carcinoma (RCC) in human patients who have received prior anti -angiogenic therapy using CABOMETYX, a kinase inhibitor.
(FR) La présente invention concerne un procédé de traitement du cancer avancé à cellules rénales (RCC) chez des patients humains ayant reçu une thérapie anti-angiogénique antérieure à l'aide de CABOMETYX, un inhibiteur de kinase.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)