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1. (WO2017181183) PLASMA-BASED DETECTION OF ANAPLASTIC LYMPHOMA KINASE (ALK) NUCLEIC ACIDS AND ALK FUSION TRANSCRIPTS AND USES THEREOF IN DIAGNOSIS AND TREATMENT OF CANCER
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Pub. No.:    WO/2017/181183    International Application No.:    PCT/US2017/027944
Publication Date: 19.10.2017 International Filing Date: 17.04.2017
IPC:
C12Q 1/68 (2006.01)
Applicants: EXOSOME DIAGNOSTICS, INC. [US/US]; Riverside Technology Center 840 Memorial Drive, Suite 3 Cambridge, Massachusetts 02139 (US)
Inventors: SKOG, Johan Karl Olov; (US).
NOERHOLM, Mikkel; (DE).
BRINKMAN, Kay; (US).
CASTELLANOS-RIZALDOS, Elena; (US).
HURLEY, James; (US)
Agent: KARNAKIS, Jennifer A.; (US).
ELRIFI, Ivor; (US)
Priority Data:
62/322,982 15.04.2016 US
Title (EN) PLASMA-BASED DETECTION OF ANAPLASTIC LYMPHOMA KINASE (ALK) NUCLEIC ACIDS AND ALK FUSION TRANSCRIPTS AND USES THEREOF IN DIAGNOSIS AND TREATMENT OF CANCER
(FR) DÉTECTION PAR PLASMA D'ACIDES NUCLÉIQUES DE KINASE DE LYMPHOME ANAPLASIQUE (ALK) ET DE TRANSCRITS DE FUSION D'ALK ET LEURS UTILISATIONS DANS LE DIAGNOSTIC ET LE TRAITEMENT DU CANCER
Abstract: front page image
(EN)The present invention relates generally to the field of biomarker analysis, particularly determining gene expression signatures from biological samples, including plasma samples.
(FR)La présente invention concerne d'une manière générale le domaine de l'analyse des biomarqueurs, en particulier la détermination des signatures d'expression génique à partir d'échantillons biologiques, y compris des échantillons de plasma.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)