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1. (WO2017181166) MICRORNA-294 AND LIN28A AS A DRIVER OF CARDIAC TISSUE PROLIFERATION IN RESPONSE TO PATHOLOGICAL INJURY
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/181166    International Application No.:    PCT/US2017/027876
Publication Date: 19.10.2017 International Filing Date: 17.04.2017
IPC:
A61K 35/12 (2015.01), A61K 35/26 (2015.01), A61K 35/28 (2015.01), A61K 39/00 (2006.01), C12N 1/00 (2006.01), C12N 5/07 (2010.01)
Applicants: TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION [US/US]; Broad & Montgomery Avenue Philadelphia, PA 19122 (US)
Inventors: KHAN, Mohsin; (US).
KISHORE, Raj; (US)
Agent: NGUYEN, Quang, D.; (US).
ARTIS, Ryan; (US).
CAMPBELL, Christopher; (US).
CHEN, Ming; (US).
ALLEN, Justin; (US)
Priority Data:
62/323,002 15.04.2016 US
Title (EN) MICRORNA-294 AND LIN28A AS A DRIVER OF CARDIAC TISSUE PROLIFERATION IN RESPONSE TO PATHOLOGICAL INJURY
(FR) MICROARN-294 ET LIN28A COMME STIMULATEURS DE LA PROLIFÉRATION DU TISSU CARDIAQUE EN RÉPONSE À UNE LÉSION PATHOLOGIQUE
Abstract: front page image
(EN)The invention provides one or more of miR-290 family and Lin28a modified cardiac progenitor cell based therapies for the treatment of myocardial infarction. Exosomes derived from one or more of miR-290 family and Lin28a modified cardiac progenitor cells can also be used in cardiac therapy.
(FR)L'invention concerne des thérapies à base de cellules progénitrices cardiaques modifiées par un ou plusieurs membres de la famille miR-290 et par Lin28a pour le traitement de l'infarctus du myocarde. Des exosomes dérivés d'une ou de plusieurs des cellules souches cardiaques modifiées par les membres de la famille miR-290 et par Lin28a peuvent également être utilisés en thérapeutique cardiaque.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)