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1. (WO2017181149) METHODS OF TREATING BREAST CANCER
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/181149    International Application No.:    PCT/US2017/027812
Publication Date: 19.10.2017 International Filing Date: 14.04.2017
IPC:
A61K 38/00 (2006.01), A61K 38/16 (2006.01), A61K 47/48 (2006.01), A61K 49/00 (2006.01), A61P 35/00 (2006.01), C07K 14/00 (2006.01)
Applicants: BLAZE BIOSCIENCE, INC. [US/US]; 530 Fairview Avenue North, Suite 1400 Seattle, WA 98109 (US)
Inventors: HANSEN, Stacey, J.; (US).
NOVAK, Julia, E.; (US)
Agent: ADVANI, Raj; (US).
AMJADI, Nellie; (US).
AGRAWAL, Trisha; (US).
ALMEDA, Nellie; (US).
HOLZAPFEL, Keli, L.; (US)
Priority Data:
62/323,522 15.04.2016 US
62/485,830 14.04.2017 US
Title (EN) METHODS OF TREATING BREAST CANCER
(FR) MÉTHODES DE TRAITEMENT DU CANCER DU SEIN
Abstract: front page image
(EN)Compositions and formulations comprising chlorotoxin conjugate compounds are provided, including native and modified variants of chlorotoxin peptide conjugated to detectable agents or active agents. Methods of detecting and treating ductal carcinoma in situ breast cancer, invasive ductal carcinoma breast cancer, lobular carcinoma in situ, invasive lobular carcinoma, and triple-negative breast cancer with chlorotoxin conjugate compounds are also provided, including methods of imaging tumor tissues and cells.
(FR)L'invention concerne des compositions et des formulations comprenant des composés conjugués de chlorotoxine, notamment des composés natifs et des variants modifiés du peptide chlorotoxine conjugués à des agents détectables ou à des agents actifs. L'invention concerne également des méthodes de détection et de traitement d'un cancer du sein à carcinome canalaire in situ, d'un cancer du sein à carcinome canalaire invasif, d'un carcinome lobulaire in situ, d'un carcinome lobulaire invasif, et d'un cancer du sein triple négatif à l'aide de composés conjugués de chlorotoxine, notamment des procédés d'imagerie de tissus et de cellules tumoraux.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)