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1. (WO2017181148) ICOS LIGAND VARIANT IMMUNOMODULATORY PROTEINS AND USES THEREOF
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/181148    International Application No.:    PCT/US2017/027811
Publication Date: 19.10.2017 International Filing Date: 14.04.2017
IPC:
C07K 14/705 (2006.01)
Applicants: ALPINE IMMUNE SCIENCES, INC. [US/US]; 201 Elliott Ave. West Suite 230 Seattle, WA 98119 (US)
Inventors: SWANSON, Ryan; (US).
KORNACKER, Michael; (US)
Agent: POTTER, Karen; (US).
AIKEN, Charity; (US).
AHN, Sejin; (US).
BANKO, Max; (US).
ARJOMAND, Mehran; (US)
Priority Data:
62/323,608 15.04.2016 US
62/394,745 14.09.2016 US
62/410,842 20.10.2016 US
62/475,162 22.03.2017 US
62/472,568 16.03.2017 US
Title (EN) ICOS LIGAND VARIANT IMMUNOMODULATORY PROTEINS AND USES THEREOF
(FR) PROTÉINES IMMUNOMODULATRICES À VARIANTS DU LIGAND ICOS ET LEURS UTILISATIONS
Abstract: front page image
(EN)Provided herein are immunomodulatory proteins comprising ICOSL variants and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.
(FR)L'invention concerne des protéines immunomodulatrices comprenant des variants de ICOSL, et des acides nucléiques codant pour ces protéines. Les protéines immunomodulatrices présentent une utilité thérapeutique pour divers états immunologiques et oncologiques. La présente invention concerne des compositions et des méthodes de fabrication et d'utilisation de ces protéines.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)