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1. (WO2017180854) NOVEL AAV8 MUTANT CAPSIDS AND COMPOSITIONS CONTAINING SAME
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2017/180854 International Application No.: PCT/US2017/027392
Publication Date: 19.10.2017 International Filing Date: 13.04.2017
IPC:
C12N 15/86 (2006.01) ,C12N 15/864 (2006.01) ,C07K 7/06 (2006.01) ,C07K 14/005 (2006.01)
Applicants: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA[US/US]; 3160 Chestnut Street Suite 200 Philadelphia, PA 19104, US
Inventors: WILSON, James, M.; US
WANG, Qiang; US
Agent: SCHALLER, Colleen, M.; US
BAK, William; US
KODROFF, Cathy, A.; US
SMITH, George, A.; US
KITA, Stanley, B.; US
DUMINIAK, Robert, J.; US
Priority Data:
62/323,38915.04.2016US
Title (EN) NOVEL AAV8 MUTANT CAPSIDS AND COMPOSITIONS CONTAINING SAME
(FR) NOUVELLES CAPSIDES MUTANTES DE AAV8 ET COMPOSITIONS LES CONTENANT
Abstract: front page image
(EN) Provided herein are AAV8 mutant capsids and rAAV comprising the same. In one embodiment, vectors employing the AAV8 mutant capsid show increased transduction in a selected tissue as compared to AAV8.
(FR) L'invention concerne des capsides mutantes de AAV8 et des virus adéno-associés recombinants (rAAV) les comprenant. Dans un mode de réalisation, les vecteurs utilisant la capside mutante de AAV8 présentent une transduction accrue dans un tissu sélectionné par rapport à AAV8.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)