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1. (WO2017180715) INSECTICIDAL POLYPEPTIDES HAVING IMPROVED ACTIVITY SPECTRUM AND USES THEREOF

Pub. No.:    WO/2017/180715    International Application No.:    PCT/US2017/027160
Publication Date: Fri Oct 20 01:59:59 CEST 2017 International Filing Date: Thu Apr 13 01:59:59 CEST 2017
IPC: C07K 14/325
C12N 15/82
A01N 3/02
Applicants: PIONEER HI-BRED INTERNATIONAL, INC.
Inventors: HORN, Caroline
LAU, Sabina
IZUMI WILLCOXON, Michi
YAMAMOTO, Takashi
ZHENG, Yi
Title: INSECTICIDAL POLYPEPTIDES HAVING IMPROVED ACTIVITY SPECTRUM AND USES THEREOF
Abstract:
The disclosure provides nucleic acids, and variants and fragments thereof, derived from strains of Bacillus thuringiensis encoding variant polypeptides having increased pesticidal activity against insect pests, including Lepidoptera and Coleopteran. Particular embodiments of the disclosure provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, DNA constructs, and transformed microorganisms and plants comprising a nucleic acid of the embodiments. These compositions find use in methods for controlling pests, especially plant pests.