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1. (WO2017180714) ANTIFUNGAL ACTIVITY OF lRON SEQUESTERING POLYMERS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/180714    International Application No.:    PCT/US2017/027158
Publication Date: 19.10.2017 International Filing Date: 12.04.2017
IPC:
A61K 31/785 (2006.01)
Applicants: UNIVERSITY OF KANSAS [US/US]; 1450 Jayhawk Boulevard 245 Strong Hall Lawrence, KS 66045 (US)
Inventors: BERKLAND, Cory; (US).
QIAN, Jian; (US).
SULLIVAN, Bradley, Paul; (US)
Agent: GIBSON, Matthew, S.; (US)
Priority Data:
62/321,275 12.04.2016 US
Title (EN) ANTIFUNGAL ACTIVITY OF lRON SEQUESTERING POLYMERS
(FR) ACTIVITÉ ANTIFONGIQUE DE POLYMÈRES SÉQUESTRANT LE FER
Abstract: front page image
(EN)A polymeric metal sequestrant providing antifungal activity is provided. The polymeric metal sequestrant comprises a polyamine polymer covalently coupled to a chelator, wherein the chelator has a benzene ring with more than one hydroxyl group at any position that is free. The polymeric metal sequestrant is effective in inhibiting and preventing fungal infections and displays synergistic effects in combination with traditional antifungal agents.
(FR)La présente invention concerne un séquestrant de métal polymère produisant une activité antifongique. Le séquestrant de métal polymère comprend un polymère de polyamine couplé de façon covalente à un chélateur, le chélateur comportant un cycle benzénique avec plus d'un groupe hydroxyle à une quelconque position qui est libre. Le séquestrant de métal polymère est efficace dans l’inhibition et la prévention d’infections fongiques et présente des effets synergiques en combinaison avec des agents antifongiques classiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)