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1. (WO2017180708) SYSTEMS, METHODS AND PRODUCTS FOR MINIMIZING TISSUE REACTIONS AND TISSUE INJURY AT AN INFUSION SITE
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2017/180708 International Application No.: PCT/US2017/027146
Publication Date: 19.10.2017 International Filing Date: 12.04.2017
IPC:
C07K 14/62 (2006.01) ,A61K 38/28 (2006.01) ,A61K 9/08 (2006.01)
Applicants: CELL AND MOLECULAR TISSUE ENGINEERING, LLC[US/US]; 14 Highwood Drive Avon, CT 06001, US
Inventors: KLUEH, Ulrike, W.; US
KREUTZER, Donald, L.; US
Agent: COVELLO, Diane, F.; ALIX, YALE & RISTAS, LLP 150 Trumbull Street, Sixth Floor Hartford, CT 06103-2721, US
Priority Data:
62/321,52312.04.2016US
62/321,59712.04.2016US
Title (EN) SYSTEMS, METHODS AND PRODUCTS FOR MINIMIZING TISSUE REACTIONS AND TISSUE INJURY AT AN INFUSION SITE
(FR) SYSTÈMES, PROCÉDÉS ET PRODUITS PERMETTANT DE RÉDUIRE AU MINIMUM LES RÉACTIONS TISSULAIRES ET LES LÉSIONS TISSULAIRES AU NIVEAU D'UN SITE DE PERFUSION
Abstract: front page image
(EN) Products, systems and methods are disclosed for lowering the concentrations of at least one of preservatives and fibrils in a liquid insulin composition. One method comprises replacing at least a portion of at least one of phenol and m-cresol with at least one of cyclodextrins, cyclodextrin polymers, cyclodextrin beads, and an ion exchange resin.
(FR) L'invention concerne des produits, des systèmes et des procédés permettant d'abaisser les concentrations des agents conservateurs et/ou des fibrilles dans une composition d'insuline liquide. Un procédé comprend le remplacement d'au moins une partie du phénol et/ou du m-crésol par des cyclodextrines, des polymères de cyclodextrines, des billes de cyclodextrines et/ou une résine échangeuse d'ions.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)