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1. (WO2017180694) CAS9 FUSION MOLECULES, GENE EDITING SYSTEMS, AND METHODS OF USE THEREOF
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2017/180694 International Application No.: PCT/US2017/027126
Publication Date: 19.10.2017 International Filing Date: 12.04.2017
IPC:
C12N 15/10 (2006.01) ,C12N 15/62 (2006.01) ,C12N 15/63 (2006.01) ,C12N 9/22 (2006.01)
Applicants: EDITAS MEDICINE, INC.[US/US]; 11 Hurley Street Cambridge, MA 02141, US
Inventors: COTTA-RAMUSINO, Cecilia; US
JAYARAM, Hariharan; US
ZURIS, John, Anthony; US
Agent: ZACHARAKIS, Maria Laccotripe; US
BELT, Erik, P.; US
ACETO, Donato; US
ZACHARAKIS, Maria, Laccortipe; US
BAI, Mei; US
Priority Data:
62/322,02613.04.2016US
Title (EN) CAS9 FUSION MOLECULES, GENE EDITING SYSTEMS, AND METHODS OF USE THEREOF
(FR) SYSTÈMES D'ÉDITION DE GÈNES DE MOLÉCULES DE FUSION CAS9 ET LEURS PROCÉDÉS D'UTILISATION
Abstract:
(EN) Disclosed herein are enzymatically active Cas9 (eaCas9) fusion molecules, comprising an eaCas9 molecule linked, e.g., covalently or non-covalently, to a template nucleic acid; gene editing systems comprising the eaCas9 fusion molecules, and methods of use thereof.
(FR) L'invention concerne des molécules de fusion Cas9 enzymatiquement actives (eaCas9), comprenant une molécule eaCas9 liée, par exemple, de manière covalente ou non covalente, à une molécule patron d'acide nucléique; des systèmes d'édition de gènes comprenant les molécules de fusion eaCas9, et leurs procédés d'utilisation.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)