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1. (WO2017180361) DIFFERENTIATION OF PLURIPOTENT STEM CELLS TO INTESTINAL MIDGUT ENDODERM CELLS
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Pub. No.: WO/2017/180361 International Application No.: PCT/US2017/025847
Publication Date: 19.10.2017 International Filing Date: 04.04.2017
IPC:
C12N 5/071 (2010.01) ,A61K 35/38 (2015.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07
Animal cells or tissues
071
Vertebrate cells or tissues, e.g. human cells or tissues
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
12
Materials from mammals or birds
37
Digestive system
38
Stomach; Intestine
Applicants: JANSSEN BIOTECH, INC.[US/US]; 800/850 Ridgeview Drive Horsham, Pennsylvania 19044, US
Inventors: RIECK, Sebastian; US
REZANIA, Alireza; US
Agent: SHIRTZ, Joseph F.; US
GIANNESCHI, Lois; US
Priority Data:
62/322,63614.04.2016US
Title (EN) DIFFERENTIATION OF PLURIPOTENT STEM CELLS TO INTESTINAL MIDGUT ENDODERM CELLS
(FR) DIFFÉRENCIATION DE CELLULES SOUCHES PLURIPOTENTES EN CELLULES DE L'ENDODERME DE L'INTESTIN MOYEN
Abstract:
(EN) Cell populations of intestinal midgut endoderm cells and methods of generating the cells expressing markers characteristic of intestinal endoderm lineage are disclosed. Methods of treating conditions such as diabetes are also disclosed.
(FR) L'invention concerne des populations cellulaires de cellules d'endoderme de l'intestin moyen et des procédés de génération des cellules exprimant des marqueurs caractéristiques de la lignée de l'endoderme intestinal. L'invention concerne également des méthodes de traitement de pathologies telles que le diabète.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)