Search International and National Patent Collections

1. (WO2017179976) MEANS AND METHODS FOR THE N-DEALKYLATION OF AMINES

Pub. No.:    WO/2017/179976    International Application No.:    PCT/NL2017/050226
Publication Date: Fri Oct 20 01:59:59 CEST 2017 International Filing Date: Fri Apr 14 01:59:59 CEST 2017
IPC: C07C 213/08
C07D 451/12
C07C 231/12
B01J 23/52
Applicants: RIJKSUNIVERSITEIT GRONINGEN
STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN
Inventors: YUAN, Tao
BISCHOFF, Rainer Paul Hermann
PERMENTIER, Hjalmar Petrus
Title: MEANS AND METHODS FOR THE N-DEALKYLATION OF AMINES
Abstract:
The invention relates to improved means and methods for N- dealkylation of alkylated amines. Provided is a method for the catalytic N- dealkylation of an N-alkylated amine substrate, comprising incubating said amine substrate in a suitable solvent in the presence of a nanoporous gold (NPG) surface and allowing for the formation of an N-dealkylation product. Also provided is a reaction mixture comprising an N-alkylated amine substrate in a suitable solvent and a NPG surface.