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1. (WO2017179045) INDOCYANINE GREEN FORMULATIONS AND METHODS FOR INTRAOPERATIVE LOCALIZATION OF RECTAL TUMORS

Pub. No.:    WO/2017/179045    International Application No.:    PCT/IL2017/050431
Publication Date: Fri Oct 20 01:59:59 CEST 2017 International Filing Date: Mon Apr 10 01:59:59 CEST 2017
IPC: A61K 49/00
Applicants: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM
THE MEDICAL RESEARCH, INFRASTRUCTURE AND HEALTH SERVICES FUND OF THE TEL-AVIV MEDICAL CENTER
Inventors: NIZRI, Eran
EYAL, Sara
MAGDASSI, Shlomo
Title: INDOCYANINE GREEN FORMULATIONS AND METHODS FOR INTRAOPERATIVE LOCALIZATION OF RECTAL TUMORS
Abstract:
The present invention relates to an imaging composition for use in localization, e.g., intraoperative localization, of a tumor, in particular a gastrointestinal or colon tumor, e.g., in intraoperative localization of a rectal tumor during laparoscopic anterior resection, which comprises particles each comprising a phospholipid, wherein a near infrared (NIR) fluorescent probe is non-covalently linked to said particle.