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Pub. No.:    WO/2017/178829    International Application No.:    PCT/GB2017/051045
Publication Date: 19.10.2017 International Filing Date: 13.04.2017
C07K 14/605 (2006.01), A61K 38/26 (2006.01), G01N 33/68 (2006.01)
Applicants: IMPERIAL INNOVATIONS LIMITED [GB/GB]; 52 Princes Gate Exhibition Road London Greater London SW7 2PG (GB)
Inventors: BLOOM, Stephen Robert; (GB).
JONES, Benjamin John; (GB)
Agent: ABEL & IMRAY; (GB).
BRADY, Paul Andrew; (GB).
HEWSON, Timothy John; (GB).
COGGINS, Julia Frances; (GB)
Priority Data:
1606673.0 15.04.2016 GB
1606754.8 18.04.2016 GB
Abstract: front page image
(EN)Peptide hormone analogues of formulae (I) to (IV) are provided comprising amino acid substitutions relative to the native sequences at one or more of positions 1 to 5. Also provided herein are pharmaceutical compositions comprising said analogues, and methods of using said analogues for the treatment of conditions such as obesity and diabetes.
(FR)L'invention concerne des analogues d'hormones peptidiques représentés par les formules (I) à (IV), comprenant des substitutions d'acides aminés par rapport aux séquences natives à une ou plusieurs des positions 1 à 5. L'invention concerne également des compositions pharmaceutiques comprenant lesdits analogues, et des procédés d'utilisation desdits analogues pour le traitement d'états pathologiques tels que l'obésité et le diabète.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)