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1. (WO2017178820) ADENOSINE RECEPTOR MODULATORS FOR THE TREATMENT OF CIRCADIAN RHYTHM DISORDERS

Pub. No.:    WO/2017/178820    International Application No.:    PCT/GB2017/051029
Publication Date: Fri Oct 20 01:59:59 CEST 2017 International Filing Date: Thu Apr 13 01:59:59 CEST 2017
IPC: A61K 31/44
A61K 31/4439
A61K 31/505
A61K 31/517
A61K 31/519
A61K 31/53
A61P 43/00
Applicants: OXFORD UNIVERSITY INNOVATION LIMITED
Inventors: VASUDEVAN, Dr. Sridhar
JAGANNATH, Dr. Aarti
FOSTER, Prof Russell
Title: ADENOSINE RECEPTOR MODULATORS FOR THE TREATMENT OF CIRCADIAN RHYTHM DISORDERS
Abstract:
The present invention relates to the use of adenosine receptor modulators to affect the circadian rhythm, in particular, to the use of such modulators for the treatment of circadian rhythm disorders. In particular, the invention relates to a com position com prising at least one selective adenosine receptor modulator, wherein said composition modulates two or three, but not al l of adenosine receptor subtypes A1, A2A, A2B and/or A3 for use in the treatment of circadian rhythm disorders or for modulating a biological clock.