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1. (WO2017177160) FORMULATION FOR USE IN A METHOD OF TREATMENT OF PAIN
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Pub. No.: WO/2017/177160 International Application No.: PCT/US2017/026640
Publication Date: 12.10.2017 International Filing Date: 07.04.2017
IPC:
A61K 31/195 (2006.01) ,A61K 31/167 (2006.01) ,A61P 25/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
195
having an amino group
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
16
Amides, e.g. hydroxamic acids
165
having aromatic rings, e.g. colchicine, atenolol, progabide
167
having the nitrogen atom of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
Applicants:
NEVAKAR INC. [US/US]; NJ Center of Excellence 1019 Route 202-206, Building K Bridgewater, NJ 08807, US
Inventors:
KHURANA, Varun; US
YADAV, Vivek; US
LIPMAN, Jack Martin; US
ZHANG, Tao; US
ILITCHEV, Iouri V.; US
HINGORANI, Tushar; US
SOPPIMATH, Kumaresh; US
PURI, Navneet; US
Agent:
KULKARNI, Sima Singadia; US
Priority Data:
62/319,52607.04.2016US
Title (EN) FORMULATION FOR USE IN A METHOD OF TREATMENT OF PAIN
(FR) FORMULATION DESTINÉE À ÊTRE UTILISÉE DANS UNE MÉTHODE DE TRAITEMENT DE LA DOULEUR
Abstract:
(EN) Formulations, methods of manufacturing, methods of stabilizing, kits, and uses as medicament are provided, for example for the treatment of pain. The formulations can comprise gabapentin optionally combined with at least one non-opioid pain drug in an aqueous carrier. The pharmaceutical formulation can have a pH of about 2.0 to about 10.0. The at least one non-opioid pain drug can be acetaminophen. The components can be included in any amount suitable for purposes of obtaining properties desirable for an injectable infusion, for example an intravenous infusion.
(FR) L'invention concerne des formulations, des procédés de fabrication, des procédés de stabilisation, des kits, ainsi que leurs utilisations en tant que médicament, par exemple dans le traitement de la douleur. Les formulations selon l'invention peuvent contenir de la gabapentine facultativement combinée à au moins un médicament anti-douleur non opioïde dans un excipient aqueux. La formulation pharmaceutique selon l'invention peut présenter un pH compris entre environ 2 et environ 10. Ledit médicament anti-douleur non opioïde au moins peut être de l'acétaminophène. Les composants peuvent être contenus dans n'importe quelle quantité appropriée permettant d'obtenir les propriétés souhaitées pour une perfusion injectable, par exemple une perfusion intraveineuse.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)