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1. (WO2017176792) METHODS OF PREVENTING OR REDUCING A FIBROTIC RESPONSE USING CSF 1R INHIBITORS

Pub. No.:    WO/2017/176792    International Application No.:    PCT/US2017/025991
Publication Date: Fri Oct 13 01:59:59 CEST 2017 International Filing Date: Wed Apr 05 01:59:59 CEST 2017
IPC: A61F 2/02
A61K 31/505
A61K 31/47
Applicants: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
Inventors: DOLOFF, Joshua, C.
FARAH, Shady
VEISEH, Omid
VEGAS, Arturo, J.
LANGER, Robert, S.
ANDERSON, Daniel, G.
Title: METHODS OF PREVENTING OR REDUCING A FIBROTIC RESPONSE USING CSF 1R INHIBITORS
Abstract:
Described herein are methods of preventing or reducing fibrosis comprising administering CSF1R inhibitors, coating formulations comprising CSF1R inhibitors, coatings comprising CSF1R inhibitors for implantable medical devices, CSF1R inhibitor coated implantable medical devices, as well as corresponding embodiments comprising additional agents.