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1. (WO2017176764) SYSTEM, DEVICE AND METHOD FOR ELECTROPORATION OF CELLS

Pub. No.:    WO/2017/176764    International Application No.:    PCT/US2017/025956
Publication Date: Fri Oct 13 01:59:59 CEST 2017 International Filing Date: Wed Apr 05 01:59:59 CEST 2017
IPC: C12M 1/42
C12N 5/071
C12N 5/10
C12M 3/00
C12N 13/00
C12N 15/09
Applicants: CYTEQUEST, INC.
Inventors: CORSO, Thomas, N.
Title: SYSTEM, DEVICE AND METHOD FOR ELECTROPORATION OF CELLS
Abstract:
A system, device and method for electroporation of living cells and the introduction of selected molecules into the cells utilizes a fluidic system where living cells and biologically active molecules flow through a channel that exposes them to electric fields, causing the molecules to be transferred across the cell membrane. The device is structured in a manner that allows precise control of the cells location, motion, and exposure to electric fields within the flow channel device. The method is particularly well suited for the introduction of DNA, RNA, drug compounds, and other biologically active molecules into living cells.