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1. (WO2017176756) COMPOSITIONS AND METHODS FOR TREATING CANCER
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/176756    International Application No.:    PCT/US2017/025945
Publication Date: 12.10.2017 International Filing Date: 04.04.2017
IPC:
A61K 31/517 (2006.01), C07D 239/91 (2006.01), C07D 405/12 (2006.01)
Applicants: CASE WESTERN RESERVE UNIVERSITY [US/US]; 10900 Euclid Avenue Cleveland, Ohio 44106 (US)
Inventors: DIFEO, Analisa; (US).
NARLA, Goutham; (US).
ARMSTRONG, Amy D.; (US)
Agent: SUTKUS, Richard A.; (US)
Priority Data:
62/318,066 04.04.2016 US
Title (EN) COMPOSITIONS AND METHODS FOR TREATING CANCER
(FR) COMPOSITIONS ET MÉTHODES DE TRAITEMENT DU CANCER
Abstract: front page image
(EN)A method of treating cancer in a subject in need thereof includes administering to the subject therapeutically effective amounts of a PP2A activator and a BER inhibitor, such a PARP inhibitor.
(FR)L'invention concerne une méthode de traitement du cancer chez un patient le nécessitant qui consiste à administrer audit patient des quantités thérapeutiquement efficaces d'un activateur de PP2A et d'un inhibiteur de la réparation par excision de base (BER), tel qu’un inhibiteur de PARP.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)