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1. (WO2017176289) USES OF LENALIDOMIDE AND CAR T-CELLS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/176289    International Application No.:    PCT/US2016/026731
Publication Date: 12.10.2017 International Filing Date: 08.04.2016
IPC:
C07K 16/22 (2006.01), C07K 16/28 (2006.01)
Applicants: CELGENE CORPORATION [US/US]; 85 Morris Avenue Summit, NJ 07901 (US).
NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY [JP/JP]; 1, Furo-cho, Chikusa-ku Nagoya-shi, 464-8601 (JP)
Inventors: NATSUME, Atsushi; (JP).
KURAMITSU, Shunichiro; (JP).
OHNO, Masasuke; (JP)
Agent: HEBERT, Michael L.; (US)
Priority Data:
Title (EN) USES OF LENALIDOMIDE AND CAR T-CELLS
(FR) UTILISATIONS DE LÉNALIDOMIDE ET DE LYMPHOCYTES T CAR
Abstract: front page image
(EN)Provided herein are methods of using lenalidomide and modified T lymphocytes for the treatment of diseases, such as a cancer or a tumor expressing EGFRvIII, and related uses of lenalidomide for modulating T lymphocyte activation and/or proliferation.
(FR)L'invention concerne des procédés d'utilisation de lénalidomide et de lymphocytes T modifiés pour le traitement de maladies, telles qu'un cancer ou une tumeur exprimant EGFRvIII, et des utilisations associées de lénalidomide pour moduler l'activation et/ou la prolifération des lymphocytes T.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)