Search International and National Patent Collections

1. (WO2017175842) COMPOUND AND PHARMACEUTICAL COMPOSITION PERTAINING TO MODIFICATION OF SPLICING

Pub. No.:    WO/2017/175842    International Application No.:    PCT/JP2017/014420
Publication Date: Fri Oct 13 01:59:59 CEST 2017 International Filing Date: Fri Apr 07 01:59:59 CEST 2017
IPC: A61K 31/443
A61K 31/4439
A61K 31/4709
A61K 31/4725
A61K 48/00
A61P 43/00
C07D 401/04
C07D 401/12
C07D 409/04
Applicants: KYOTO UNIVERSITY
国立大学法人京都大学
Inventors: HAGIWARA Masatoshi
萩原正敏
OOE Kenji
大江賢治
SAKO Yukiya
佐古有季哉
HOSOYA Takamitsu
細谷孝充
YOSHIDA Suguru
吉田優
SUMIDA Yuto
隅田有人
Title: COMPOUND AND PHARMACEUTICAL COMPOSITION PERTAINING TO MODIFICATION OF SPLICING
Abstract:
Provided are a compound and a pharmaceutical composition pertaining to the modification of splicing, the use of these, or a method for preventing, improving, suppressing the advance of, and/or treating a genetic disease in which the compound and pharmaceutical composition are used. In one or more embodiments, a pharmaceutical composition for modifying splicing has as an active ingredient a compound represented by general formula (I) or a prodrug thereof or a pharmacologically acceptable salt thereof, said compound having the ability to inhibit the phosphorylase activity of protein kinase. X2: -(bond) or -NH-