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1. (WO2017175827) MODIFICATION METHOD TO MAINTAIN UPTAKE OF SYNTHETIC AMINO ACID IN CANCER CELLS, AND NEUTRON CAPTURE THERAPY TO PROTECT NORMAL CELLS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/175827    International Application No.:    PCT/JP2017/014366
Publication Date: 12.10.2017 International Filing Date: 06.04.2017
Chapter 2 Demand Filed:    29.11.2017    
IPC:
A61K 41/00 (2006.01), A61K 31/198 (2006.01), A61K 31/69 (2006.01), A61K 33/22 (2006.01), A61K 45/00 (2006.01), A61K 47/18 (2017.01), A61K 49/00 (2006.01), A61K 49/06 (2006.01), A61P 35/00 (2006.01)
Applicants: CANCER INTELLIGENCE CARE SYSTEMS, INC. [JP/JP]; TOC Ariake West Tower 17F, 3-5-7 Ariake, Koto-ku, Tokyo 1350063 (JP)
Inventors: IMAHORI Yoshio; (JP).
ENDOU Hitoshi; (JP).
FUJII Ryo; (JP).
TAKEYOSHI Tsuyako; (JP).
FUSHIMI Ariyoshi; (JP).
TSUJIKAWA Dai; (JP)
Agent: HIRAKI & ASSOCIATES; Atago Green Hills MORI Tower 32F, 5-1, Atago 2-chome, Minato-ku, Tokyo 1056232 (JP)
Priority Data:
2016-078453 08.04.2016 JP
Title (EN) MODIFICATION METHOD TO MAINTAIN UPTAKE OF SYNTHETIC AMINO ACID IN CANCER CELLS, AND NEUTRON CAPTURE THERAPY TO PROTECT NORMAL CELLS
(FR) PROCÉDÉ DE MODIFICATION POUR MAINTENIR L'ABSORPTION D'ACIDE AMINÉ SYNTHÉTIQUE DANS DES CELLULES CANCÉREUSES, ET THÉRAPIE PAR CAPTURE DE NEUTRONS POUR PROTÉGER DES CELLULES NORMALES
(JA) 合成アミノ酸の癌細胞内取り込みを保持する修飾法と正常細胞を保護する中性子捕捉療法
Abstract: front page image
(EN)The purpose of the present invention is to provide a means with which it is possible to selectively improve the amount of a boron-containing compound accumulated in cancer cells. The present invention pertains to the use of at least one type of amino acid and/or at least one type of amino acid transport system inhibitor, these being used to improve the amount of a boron-containing compound accumulated in cancer cells.
(FR)L’objectif de la présente invention est de fournir un moyen avec lequel il est possible d'améliorer sélectivement la quantité d'un composé contenant du bore accumulé dans des cellules cancéreuses. La présente invention concerne l'utilisation d'au moins un type d'acide aminé et/ou d'au moins un type d'inhibiteur de système de transport d'acides aminés, ceux-ci étant utilisés pour améliorer la quantité d'un composé contenant du bore accumulé dans des cellules cancéreuses.
(JA)本発明は、癌細胞における含ホウ素化合物の蓄積量を選択的に向上させることを可能とする手段を提供すること目的とする。本発明は、癌細胞における含ホウ素化合物の蓄積量を向上させるために用いられる、少なくとも1種のアミノ酸及び/又は少なくとも1種のアミノ酸輸送系阻害剤の利用に関する。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)