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1. (WO2017175747) SUPERCONTINUUM-LIGHT-GENERATING LIGHT SOURCE, SUPERCONTINUUM-LIGHT GENERATION METHOD, MULTIPHOTON-EXCITED FLUORESCENCE MICROSCOPE, AND MULTIPHOTON EXCITATION METHOD
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Pub. No.: WO/2017/175747 International Application No.: PCT/JP2017/014049
Publication Date: 12.10.2017 International Filing Date: 04.04.2017
IPC:
G01N 21/64 (2006.01) ,G01N 21/01 (2006.01) ,G02B 21/06 (2006.01) ,G02F 1/365 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21
Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible, or ultra-violet light
62
Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63
optically excited
64
Fluorescence; Phosphorescence
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21
Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible, or ultra-violet light
01
Arrangements or apparatus for facilitating the optical investigation
G PHYSICS
02
OPTICS
B
OPTICAL ELEMENTS, SYSTEMS, OR APPARATUS
21
Microscopes
06
Means for illuminating specimen
G PHYSICS
02
OPTICS
F
DEVICES OR ARRANGEMENTS, THE OPTICAL OPERATION OF WHICH IS MODIFIED BY CHANGING THE OPTICAL PROPERTIES OF THE MEDIUM OF THE DEVICES OR ARRANGEMENTS FOR THE CONTROL OF THE INTENSITY, COLOUR, PHASE, POLARISATION OR DIRECTION OF LIGHT, e.g. SWITCHING, GATING, MODULATING OR DEMODULATING; TECHNIQUES OR PROCEDURES FOR THE OPERATION THEREOF; FREQUENCY-CHANGING; NON-LINEAR OPTICS; OPTICAL LOGIC ELEMENTS; OPTICAL ANALOGUE/DIGITAL CONVERTERS
1
Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulating; Non-linear optics
35
Non-linear optics
365
in an optical waveguide structure
Applicants: USHIO DENKI KABUSHIKI KAISHA[JP/JP]; 1-6-5, Marunouchi, Chiyoda-ku, Tokyo 1008150, JP
RIKEN[JP/JP]; 2-1, Hirosawa, Wako-shi, Saitama 3510198, JP
Inventors: ICHIHARA Akira; JP
NAKANO Akihiko; JP
SAWADA Aiko; JP
OTA Aya; JP
Agent: HOTATE Koichi; JP
Priority Data:
2016-07615505.04.2016JP
2016-17860513.09.2016JP
Title (EN) SUPERCONTINUUM-LIGHT-GENERATING LIGHT SOURCE, SUPERCONTINUUM-LIGHT GENERATION METHOD, MULTIPHOTON-EXCITED FLUORESCENCE MICROSCOPE, AND MULTIPHOTON EXCITATION METHOD
(FR) SOURCE DE LUMIÈRE GÉNÉRANT DE LA LUMIÈRE SUPERCONTINUUM, PROCÉDÉ DE GÉNÉRATION DE LUMIÈRE SUPERCONTINUUM, MICROSCOPE À FLUORESCENCE PAR EXCITATION MULTIPHOTONIQUE ET PROCÉDÉ D'EXCITATION MULTIPHOTONIQUE
(JA) スーパーコンティニウム光生成光源、スーパーコンティニウム光生成方法、多光子励起蛍光顕微鏡及び多光子励起方法
Abstract:
(EN) [Problem] To provide a supercontinuum-light-generating light source which can be used in a novel application. [Solution] Ultrashort pulsed-laser light generated from a pulsed-light oscillator 1 enters a waveguide 2 via a polarization control element 3 and becomes supercontinuum light due to a nonlinear optical effect, and the supercontinuum light is compressed by a pulse compressor 7 comprising a prism pair unit 71 and emitted. The waveguide 2 comprises nonlinear fibers that exhibit normal dispersion characteristics in a wavelength region of 850-1550 nm, supercontinuum light being obtained in a spectrum that is continuous in a band having a wavelength width of at least 200 nm that is included in the wavelength region of 850-1550 nm. The time peak intensity of the supercontinuum light is at least 1 kW, the supercontinuum light being used as excitation light in a multiphoton-excited fluorescence microscope for performing fluorescence observation, etc., of a biological sample.
(FR) Le problème décrit par la présente invention est de fournir une source de lumière générant de la lumière supercontinuum qui peut être utilisée dans une nouvelle application. La solution consiste en une lumière laser pulsée ultracourte, produite par un oscillateur à lumière pulsée 1 et qui pénètre dans un guide d'ondes 2 par l'intermédiaire d'un élément de commande de la polarisation 3 et devient de la lumière supercontinuum du fait d'un effet optique non linéaire, suite à quoi la lumière supercontinuum est comprimée par un compresseur d'impulsions 7 comprenant une unité formée d'une paire de prismes 71, puis émise. Le guide d'ondes 2 comprend des fibres non linéaires qui présentent des caractéristiques de dispersion normales dans une plage de longueurs d'onde de 850-1 550 nm, la lumière supercontinuum étant obtenue dans un spectre qui est continu dans une bande présentant une largeur de longueur d'onde d'au moins 200 nm qui est incluse dans la plage des longueurs d'onde de 850-1 550 nm. L'intensité de crête dans le temps de la lumière supercontinuum est au moins égale à 1 kW, la lumière supercontinuum étant utilisée comme lumière d'excitation dans un microscope à fluorescence par excitation multiphotonique pour observer par fluorescence, etc., un échantillon biologique.
(JA) 【課題】 新たな用途に利用できるスーパーコンティニウム光生成光源を提供する。 【解決手段】 パルス光発振部1から発振された超短パルスレーザー光は、偏光制御素子3を介して導波路2に入射し、非線形光学効果によりスーパーコンティニウム光となった後、プリズムペアユニット71より成るパルス圧縮部7で圧縮されて出射する。導波路2は、850~1550nmの波長域において正常分散特性を示す非線形ファイバであり、850nm以上1550nm以下の波長域に含まれる少なくとも200nmの波長幅の帯域において連続したスペクトルのスーパーコンティニウム光が得られる。スーパーコンティニウム光の時間ピーク強度は1kW以上であり、生体試料の蛍光観察等を行う多光子励起蛍光顕微鏡において励起光として使用される。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)