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1. (WO2017174999) SYNTHETIC RETINOIDS FOR USE IN RAR MEDIATED CONDITIONS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/174999    International Application No.:    PCT/GB2017/050977
Publication Date: 12.10.2017 International Filing Date: 06.04.2017
IPC:
C07C 63/66 (2006.01), A61K 31/192 (2006.01), A61K 31/203 (2006.01), C07D 215/06 (2006.01), C07D 209/82 (2006.01), A61P 25/28 (2006.01)
Applicants: HIGH FORCE RESEARCH LIMITED [GB/GB]; Bowburn Industrial Estate Bowburn Durham DH6 5PF (GB).
UNIVERSITY OF DURHAM [GB/GB]; The Palatine Centre Stockton Road Durham DH1 3LE (GB).
THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN [GB/GB]; Regent Walk Aberdeen Aberdeenshire AB24 3FX (GB)
Inventors: WHITING, Andrew; (GB).
VALENTINE, Roy; (GB).
CHISHOLM, David; (GB).
MCCAFFERY, Peter; (GB).
GREIG, Iain; (GB).
KHATIB, Thabat; (GB)
Agent: GILHOLM, Stephen Philip; (GB)
Priority Data:
1605913.1 07.04.2016 GB
Title (EN) SYNTHETIC RETINOIDS FOR USE IN RAR MEDIATED CONDITIONS
(FR) RÉTINOÏDES SYNTHÉTIQUES DESTINÉS À ÊTRE UTILISÉS POUR DES AFFECTIONS CONDITIONNÉES PAR LE RÉCEPTEUR RAR
Abstract: front page image
(EN)There are described novel compounds of formula I: in which R1, R2, R3, R4, R5, X1 and X2 are each as herein defined, for use in the treatment or alleviation of an RAR mediated condition: and methods related thereto.
(FR)L'invention concerne de nouveaux composés de formule I : dans laquelle R1, R2, R3, R4, R5, X1 et X2 sont chacun tels que définis dans la description, lesdits composés étant destinés au traitement ou à l'atténuation d'une affection conditionnée par le récepteur RAR. L'invention concerne également des méthodes associées.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)