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Pub. No.:    WO/2017/174810    International Application No.:    PCT/EP2017/058470
Publication Date: 12.10.2017 International Filing Date: 07.04.2017
C12N 7/00 (2006.01), C12N 15/74 (2006.01)
Applicants: PHICO THERAPEUTICS LTD [GB/GB]; Babraham Hall Babraham, Babraham Cambridge CB2 4AT (GB)
Inventors: FAIRHEAD, Heather; (GB).
Agent: DANIELS, Jeffrey, Nicholas; PAGE WHITE & FARRER Bedford House John Street London Greater London WC1N 2BF (GB)
Priority Data:
1606319.0 08.04.2016 GB
Abstract: front page image
(EN)A modified bacteriophage capable of infecting a plurality of different target bacteria, which bacteriophage includes a toxin gene encoding a toxin protein which is toxic to the target bacteria; wherein the bacteriophage is lytic; and wherein the bacteriophage expresses host range determinant proteins which have a plurality of bacterial host specificities.
(FR)L'invention concerne un bactériophage modifié capable d'infecter une pluralité de différentes bactéries cibles, ledit bactériophage comprenant un gène de toxine codant pour une protéine de toxine qui est toxique pour les bactéries cibles ; le bactériophage étant lytique ; et le bactériophage exprimant des protéines déterminant la gamme d'hôtes qui ont une pluralité de spécificités des hôtes bactériens.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)