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1. (WO2017174731) GLUCONO DELTA-LACTONE FOR TREATMENT OF VAGINAL FUNGAL INFECTIONS

Pub. No.:    WO/2017/174731    International Application No.:    PCT/EP2017/058268
Publication Date: Fri Oct 13 01:59:59 CEST 2017 International Filing Date: Fri Apr 07 01:59:59 CEST 2017
IPC: A61K 9/00
A61K 31/366
A61P 31/10
Applicants: GEDEA BIOTECH AB
Inventors: ELLERVIK, Ulf
STERNER, Olov
STREVENS, Helena
MANNER, Sophie
Title: GLUCONO DELTA-LACTONE FOR TREATMENT OF VAGINAL FUNGAL INFECTIONS
Abstract:
The present invention relates to a pharmaceutical formulation for vaginal administration, wherein the formulation comprises a pharmaceutical acceptable excipient and glucono δ-lactone,wherein the glucono δ-lactoneis present in an amount of 5 to 99 wt % of the formulation. The invention also relates to a pharmaceutical formulation according to the invention for use in the prevention or treatment of a urogenital fungal infection. Furthermore, the invention relates to glucono δ-lactone (formula (III)), for use in the in the prevention or treatment of a fungal infection.