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1. (WO2017174422) CHROMATOGRAPHY MATRIX
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/174422    International Application No.:    PCT/EP2017/057482
Publication Date: 12.10.2017 International Filing Date: 30.03.2017
IPC:
B01J 20/32 (2006.01), B01J 20/286 (2006.01), B01D 15/38 (2006.01), B01J 20/26 (2006.01), B01J 20/289 (2006.01)
Applicants: GE HEALTHCARE BIOPROCESS R&D AB [SE/SE]; Björkgatan 30 751 84 Uppsala (SE)
Inventors: MALOISEL, Jean-Luc; (SE).
SÖDERMAN, Tobias, E.; (SE).
LIND, Ola; (SE).
EKLIND, Ida; (SE)
Agent: LARSSON, Anders; GE HEALTHCARE BIO-SCIENCES AB Patent Department Björkgatan 30 751 84 Uppsala (SE).
ALDENBÄCK, Ulla; (SE).
LARSSON, Anders; (SE).
SÖRBY, Lennart; (SE)
Priority Data:
1605870.3 06.04.2016 GB
Title (EN) CHROMATOGRAPHY MATRIX
(FR) MATRICE DE CHROMATOGRAPHIE
Abstract: front page image
(EN)The invention discloses a separation matrix for purification of biomacromolecules, comprising a plurality of particles (1) having a core region (2) and a shell region (3), wherein: a) said shell region is accessible to a target biomacromolecule; b) said core region is less accessible to the target biomacromolecule than the shell region; and c) the core region comprises a grafted polymer comprising residues of at least one polymerizable monomer.
(FR)L'invention concerne une matrice de séparation pour la purification de bio-macromolécules, comprenant une pluralité de particules (1) ayant une région centrale (2) et une région d'enveloppe (3). Selon l'invention : a) ladite région d'enveloppe est accessible à une bio-macromolécule cible ; b) ladite région centrale est moins accessible à la bio-macromolécule cible que la région d'enveloppe ; et c) la région centrale comprend un polymère greffé comprenant des résidus d'au moins un monomère polymérisable.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)