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1. (WO2017173932) ANTIBACTERIAL CYCLIC LIPOPEPTIDES
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.:    WO/2017/173932    International Application No.:    PCT/CN2017/078056
Publication Date: 12.10.2017 International Filing Date: 24.03.2017
Chapter 2 Demand Filed:    05.02.2018    
IPC:
C07K 7/64 (2006.01), A61K 38/12 (2006.01), A61P 31/04 (2006.01)
Applicants: VERSITECH LIMITED [CN/CN]; Room 405A, Cyberport 4 100 Cyberport Road Hong Kong (CN)
Inventors: LI, Xuechen; (CN)
Agent: CHINA PATENT AGENT (H.K.) LTD.; 22/F., Great Eagle Center 23 Harbour Road Wanchai Hong Kong (CN)
Priority Data:
15/093,950 08.04.2016 US
62/438,138 22.12.2016 US
Title (EN) ANTIBACTERIAL CYCLIC LIPOPEPTIDES
(FR) LIPOPEPTIDES CYCLIQUES ANTIBACTÉRIENS
Abstract: front page image
(EN)Cyclic lipopeptides having one or more modifications relative to daptomycin, and methods of making them are provided. The cyclic lipopeptides can be used as antibacterial agents. The daptomycin analogues are generated by chemical synthesis, which makes introduction of an unnatural amino acid and any modification into daptomycin possible. Pharmaceutical compositions and method of use thereof for the disclosed daptomycin analogues are also provided.
(FR)L'invention concerne des lipopeptides cycliques comportant une ou plusieurs modifications par rapport à la daptomycine, et leurs procédés de fabrication. Les lipopeptides cycliques peuvent être utilisés en tant qu'agents antibactériens. Les analogues de la daptomycine sont générés par synthèse chimique, ce qui rend possible l'introduction d'un acide aminé non naturel et toute modification de la daptomycine. L'invention concerne également des compositions pharmaceutiques et un procédé d'utilisation de celles-ci pour les analogues de la daptomycine.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)