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1. (WO2017172769) BIOMIMETIC ANISOTROPIC POLYMERIC PARTICLES WITH NATURALLY DERIVED CELL MEMBRANES FOR ENHANCED DRUG DELIVERY
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2017/172769 International Application No.: PCT/US2017/024542
Publication Date: 05.10.2017 International Filing Date: 28.03.2017
IPC:
A61K 9/16 (2006.01) ,A61K 9/51 (2006.01) ,A61K 49/00 (2006.01) ,A61K 39/395 (2006.01)
Applicants: THE JOHNS HOPKINS UNIVERSITY[US/US]; 3400 N. Charles Street Baltimore, Maryland 21218, US
Inventors: GREEN, Jordan J.; US
MEYER, Randall A.; US
BEN-AKIVA, Elana; US
Agent: CHILDERS, Jeffrey W.; US
Priority Data:
62/314,12728.03.2016US
Title (EN) BIOMIMETIC ANISOTROPIC POLYMERIC PARTICLES WITH NATURALLY DERIVED CELL MEMBRANES FOR ENHANCED DRUG DELIVERY
(FR) PARTICULES POLYMÈRES ANISOTROPES BIOMIMÉTIQUES AYANT DES MEMBRANES CELLULAIRES D'ORIGINE NATURELLE POUR UNE ADMINISTRATION DE MÉDICAMENT AMÉLIORÉE
Abstract:
(EN) The presently disclosed subject matter provides a biomimetic particle platform that can be used to simulate natural cells found throughout the body. The particle comprises a polymeric core of defined shape, size, and mechanical properties and a surface comprising naturally derived cell membranes, such as red blood cells or platelets. Together these features enable a level of biomimicry that can be appropriated for various drug delivery applications and cell engineering applications.
(FR) La présente invention concerne une plateforme de particules biomimétiques qui peut être utilisée pour simuler des cellules naturelles présentes dans tout le corps. La particule comprend un noyau polymère de forme, de taille et de propriétés mécaniques définies et une surface comprenant des membranes cellulaires d'origine naturelle, telles que des globules rouges ou des plaquettes. Ensemble, ces caractéristiques permettent un niveau de bioimpédance qui peut être adapté à diverses applications d'administration de médicament et d'ingénierie cellulaire.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)