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1. (WO2017172761) PHENYL UREA DERIVATIVES AS N-FORMYL PEPTIDE RECEPTOR MODULATORS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2017/172761 International Application No.: PCT/US2017/024531
Publication Date: 05.10.2017 International Filing Date: 28.03.2017
IPC:
C07C 275/28 (2006.01) ,A61K 31/17 (2006.01) ,A61P 29/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
275
Derivatives of urea, i.e. compounds containing any of the groups the nitrogen atoms not being part of nitro or nitroso groups
28
having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
16
Amides, e.g. hydroxamic acids
17
having the group N-C(O)-N or N-C(S)-N, e.g. urea, thiourea, carmustine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29
Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents; Non-steroidal antiinflammatory drugs (NSAIDs)
Applicants: ALLERGAN, INC.[US/US]; 2525 Dupont Drive Irvine, California 92612, US
Inventors: DUONG, Tien T.; US
BEARD, Richard L.; US
GARST, Michael E.; US
Agent: POTTS, Barbara; US
BASS, Jonathan Y.; US
WINE, Laura; US
CHAN, Ted; US
NASSIF, Linda; US
GERMAN, Joel; US
PHAN, Brigitte; US
SIDDIQI, Lorenz; US
BRADY, Matthew O.; US
CHIEN, Andrew; US
POCHE, Thomas F.; US
Priority Data:
62/314,10828.03.2016US
Title (EN) PHENYL UREA DERIVATIVES AS N-FORMYL PEPTIDE RECEPTOR MODULATORS
(FR) DÉRIVÉS DE PHÉNYLURÉE SERVANT DE MODULATEURS DES RÉCEPTEURS DES PEPTIDES N-FORMYLES
Abstract:
(EN) The present disclosure relates to phenyl urea derivatives useful for the treatment of inflammatory diseases, pharmaceutical compositions containing them and their use as modulators of the N-formyl peptide receptor (FPR), including FPRl and FPR2, or as selective agonists of the FPRl receptor.
(FR) La présente invention concerne des dérivés de phénylurée utiles pour le traitement de maladies inflammatoires, des compositions pharmaceutiques les contenant et leur utilisation en tant que modulateurs du récepteur de peptide N-formyle (FPR), y compris FPR1 et FPR2, ou en tant qu'agonistes sélectifs du récepteur FPR1.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)