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1. (WO2017170763) DISINTEGRABLE TABLET AND METHOD FOR MANUFACTURING SAME
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2017/170763 International Application No.: PCT/JP2017/013049
Publication Date: 05.10.2017 International Filing Date: 29.03.2017
IPC:
A61K 47/36 (2006.01) ,A23L 5/00 (2016.01) ,A61K 9/20 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
36
Polysaccharides; Derivatives thereof
[IPC code unknown for A23L 5]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
Applicants: KUREHA CORPORATION[JP/JP]; 3-3-2, Nihonbashi-Hamacho, Chuo-ku, Tokyo 1038552, JP
Inventors: KOYA, Yohei; JP
KONISHI, Mayu; JP
ONO, Saichi; JP
AGETSUMA, Mikako; JP
ITO, Shunsuke; JP
MATSUI, Yukari; JP
TAKIZAWA, Anna; JP
SHIMADA, Hironao; JP
MACHI, Yoshiki; JP
Agent: SHOBAYASHI, Masayuki; JP
HAYASHI, Kazuyoshi; JP
NIIYAMA, Yuichi; JP
Priority Data:
2016-07457901.04.2016JP
Title (EN) DISINTEGRABLE TABLET AND METHOD FOR MANUFACTURING SAME
(FR) COMPRIMÉ DÉSINTÉGRABLE ET SON PROCÉDÉ DE FABRICATION
(JA) 崩壊錠及びその製造方法
Abstract:
(EN) The purpose of the present invention is to provide a disintegrable tablet that contains an active ingredient in a large volume and yet shows excellent disintegrability. The aforesaid purpose can be achieved by providing a disintegrable tablet comprising an active ingredient and pullulan, wherein: the content of the active ingredient is 65 wt% or more relative to the disintegrable tablet; the content of pullulan is 1 wt% or more relative to the disintegrable tablet; the volume of the disintegrable tablet is 0.3 cm3 or more; and the porosity of the disintegrable tablet is 20-80%.
(FR) Le but de la présente invention est de fournir un comprimé désintégrable qui contient un principe actif en grand volume et qui présente cependant une excellente capacité de désintégration. Le but mentionné ci-dessus peut être obtenu en fournissant un comprimé désintégrable comprenant un principe actif et du pullulane, dans lequel : la teneur en principe actif est de 65 % en poids ou plus par rapport au comprimé désintégrable ; la teneur en pullulane est de 1 % en poids ou plus par rapport au comprimé désintégrable ; le volume du comprimé désintégrable est de 0,3 cm3 ou plus ; et la porosité du comprimé désintégrable est de 20 à 80 %.
(JA) 本発明の目的は、高容量の有効成分を含みつつ、優れた崩壊性を示す崩壊錠を提供することである。前記課題は、有効成分とプルランとを含む崩壊錠であって、前記有効成分の含有量は、前記崩壊錠において、65重量%以上であり、プルランの含有量は、前記崩壊錠において、1重量%以上であり、前記崩壊錠の体積は、0.3cm以上であり、前記崩壊錠の空隙率は、20~80%である、崩壊錠によって解決することができる。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)