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1. WO2017170180 - MEDIUM FOR NEURAL STEM CELLS ENHANCING NEURAL DIFFERENTIATION ABILITY

Publication Number WO/2017/170180
Publication Date 05.10.2017
International Application No. PCT/JP2017/011870
International Filing Date 23.03.2017
IPC
C12N 5/0797 2010.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07Animal cells or tissues
071Vertebrate cells or tissues, e.g. human cells or tissues
079Neural cells
0797Stem cells; Progenitor cells
CPC
C12N 2500/24
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2500Specific components of cell culture medium
05Inorganic components
10Metals; Metal chelators
20Transition metals
24Iron; Fe chelators; Transferrin
C12N 2500/32
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2500Specific components of cell culture medium
30Organic components
32Amino acids
C12N 2500/90
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2500Specific components of cell culture medium
90Serum-free medium, which may still contain naturally-sourced components
C12N 2501/115
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2501Active agents used in cell culture processes, e.g. differentation
10Growth factors
115Basic fibroblast growth factor (bFGF, FGF-2)
C12N 5/0031
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor;
0018Culture media for cell or tissue culture
0031Serum-free culture media
C12N 5/0619
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor;
06Animal cells or tissues; Human cells or tissues
0602Vertebrate cells
0618Cells of the nervous system
0619Neurons
Applicants
  • 味の素株式会社 AJINOMOTO CO., INC. [JP]/[JP]
Inventors
  • 松本 拓也 MATSUMOTO, Takuya
  • 原田 育恵 HARATA, Ikue
  • 千田 将 SENDA, Sho
Agents
  • 高島 一 TAKASHIMA, Hajime
Priority Data
2016-07196731.03.2016JP
Publication Language Japanese (JA)
Filing Language Japanese (JA)
Designated States
Title
(EN) MEDIUM FOR NEURAL STEM CELLS ENHANCING NEURAL DIFFERENTIATION ABILITY
(FR) MILIEU POUR CELLULES SOUCHES NEURALES AMÉLIORANT LA CAPACITÉ DE DIFFÉRENCIATION NEURALE
(JA) 神経分化能を亢進させる神経幹細胞用培地
Abstract
(EN)
Provided are: a medium for neural stem cells and/or neural precursor cells, said medium being substantially free from one or more amino acids selected from the group consisting of L-glutamine, L-asparagine and L-aspartic acid; a method for culturing neural stem cells and/or neural precursor cells with the use of the medium, etc.
(FR)
L'invention concerne un milieu pour les cellules souches neurales et/ou les cellules précurseurs neurales, ledit milieu étant sensiblement dépourvu d'un ou de plusieurs acides aminés sélectionnés dans le groupe constitué par la L-glutamine, la L-asparagine et l'acide L-aspartique, ainsi qu'une méthode de culture de cellules souches neurales et/ou de cellules précurseurs neurales à l'aide du milieu, etc.
(JA)
本発明は、L-グルタミン、L-アスパラギン及びL-アスパラギン酸からなる群より選択される1以上のアミノ酸を実質的に含まない神経幹細胞及び/又は神経前駆細胞培地、及び当該培地を用いた神経幹細胞及び/又は神経前駆細胞の培養方法等を提供する。
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