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1. (WO2017169978) METHOD FOR PRODUCING PURIFIED FELINE ERYTHROPOIETIN

Pub. No.:    WO/2017/169978    International Application No.:    PCT/JP2017/011217
Publication Date: Fri Oct 06 01:59:59 CEST 2017 International Filing Date: Wed Mar 22 00:59:59 CET 2017
IPC: C07K 14/505
C12N 15/09
Applicants: KANEKA CORPORATION
株式会社カネカ
Inventors: WATANABE Hiroyuki
渡邉 裕幸
ADACHI Satoshi
安達 智
KYOGOKU Kenji
京極 健司
ISHIGURO Kojiro
石黒 康二朗
SASAKI Takahide
佐々木 隆英
Title: METHOD FOR PRODUCING PURIFIED FELINE ERYTHROPOIETIN
Abstract:
The purpose of the present invention is to provide an improved means for producing purified feline erythropoietin (fEPO). This method for producing purified fEPO includes: a pH adjustment step for adjusting the pH of a protein solution including fEPO to within a range of 4-7; and a purification step for bringing the protein solution, the pH of which was adjusted in the pH adjustment step, into contact with a carrier provided with cation exchange groups, adsorbing the fEPO, and then eluting the fEPO from the carrier.